Research Publications

The Omnical Indirect Calorimetry system has supported numerous research studies

The Omnical has supported numerous research studies in the field of energy metabolism ranging from resting metabolism to maximal exercise testing and nutritional studies. It has been independently tested and validated over the years. All publications in which the Omnical has been used during the interventions are listed below.

The publications can be sorted according to the best suited category for you. The entire list can be viewed by clicking on next below the list.

List of research publications (sorting on the different categories):

Authors Year of PublicationTitleJournalDesignKeywordsDOI-link
Bas Van Hooren,Maartje Cox,Gerard Rietjens,Guy Plasqui2022Determination of energy expenditure in professional cyclists using power data: validation against doubly‐labelled waterScandinavian Journal of Medicine & Science In SportsResearch Paperendurance athletes, energy expenditure, indirect calorimetry, physical activity level, professional cyclists
J.M.A.Alcantara, J.E.Galgani, L.Jurado-Fasoli, M.Dote-Montero, E.Merchan-Ramirez, E.Ravussin, J.R.Ruiz, G. Sanchez-Delgado2022Validity of four commercially available metabolic carts for assessing resting metabolic rate and respiratory exchange ratio in non-ventilated humansClinical NutritionResearch PaperIndirect calorimetry, Reliability, Basal metabolic rate
Wei Luo,Rick Kramer,Yvonne de Kort,Pascal Rense,Wouter van Marken Lichtenbelt2022The effects of a novel personal comfort system on thermal comfort, physiology and perceived indoor environmental quality, and its health implications - Stimulating human thermoregulation without compromising thermal comfortIndoor AirResearch Paperdrifting temperature, health indoor, air quality personal comfort system, thermal comfort thermoregulation
Kyra Theunissen, Bas Van Hooren, Guy Plasqui, Kenneth Meijer2022Dataset of energetics and biomechanics of self-paced and fixed speed treadmill walking at multiple speedsGait & PostureResearch PaperGait Biomechanics Energy cost of walking Self-paced treadmill Energy expenditure Kinematics
Juan M. A. Alcantara,?Guillermo Sanchez-Delgado,?Lucas Jurado-Fasoli?&?Jonatan R. Ruiz2022Reproducibility of the energy metabolism response to an oral glucose tolerance test: influence of a postcalorimetric correction procedureEuropean Journal of NutritionResearch PaperIndirect calorimetry, Reliability, Postprandial metabolism, Glucose tolerance, Metabolic cart
Jordi P. D. Kleinloog ,Stephen P. G. A. van Laar, Paul F. M. Schoffelen, Guy Plasqui2021Validity and reproducibility of VO2max testing in a respiration chamberScandinavian Journal of Medicine & Science In SportsResearch Papercycle ergometer, exercise maximal, oxygen consumption, Omnical respiration, chamber validity
Bas van Hooren, Jasper Most, Eline Collombon, Henrietta Nieminen, Guy Plasqui2022A New Approach to Improve the Validity of Doubly Labeled Water to Assess CO2 Production during High-Energy TurnoverMedicine & Science in Sports & ExercisResearch PaperENERGY EXPENDITURE, ROOM INDIRECT CALORIMETRY, DOUBLY LABELED WATER, HIGH-ENERGY TURNOVER, VALIDITYdoi: 10.1249/MSS.0000000000002865
Sabine Daemen, Nynke van Polanen, Lena Bilet, Esther Phielix, Esther Moonen-Kornips, Vera B. Schrauwen-Hinderling, Patrick Schrauwen, and Matthijs K. C. Hesselink2021Postexercise changes in myocellular lipid droplet characteristics of young lean individuals are affected by circulatory nonesterified fatty acids?American Physiological Society.Research Paperexercise lipid, droplets, muscle
ADAM VAN CASTEREN, JONATHAN R. CODD, KORNELIUS KUPCZIK, GUY PLASQUI, WILLIAM I. SELLERS, AND AMANDA G. HENRY 2022The cost of chewing: The energetics and evolutionary significance of mastication in humansSCIENCE ADVANCESResearch PaperMetabolism, mastication, EE
Kenneth Pasmans, Ruth C.R. Meex, Jorn Trommelen, Joan M.G. Senden, Elaine E. Vaughan, Luc J.C. van Loon and Ellen E. Blaak2021L-arabinose co-ingestion delays glucose absorption derived from sucrose in healthy men and women: a double-blind, randomised crossover trialBritish Journal of NutritionResearch PaperHealthy adults, Sugar, Sweetener, Sugar-sweetened beverage, Glucose metabolism, Insulin, Indirect calorimetry, Steady energy
Froukje Vanweert, Michael Neinast, Edmundo Erazo Tapia, Tineke van de Weijer, Joris Hoeks, Vera B. Schrauwen-Hinderling, Megan C. Blair, Marc R. Bornstein, Matthijs K. C. Hesselink, Patrick Schrauwen, Zoltan Arany & Esther Phielix2022A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetesNature Communications Research Paperdiabetes, metabolism
Juan J. Guerrero-Pinz?n, Juan M.A. Alcantaran,Gustavo Garc?a-Buendia, Sol Moch?n-Benguigui, Mauricio Ram?rez-Maldonado, Jonatan R. Ruiz &Lucas Jurado-Fasoli2022A nutritional intervention for moderate altitude endurance preparation: A case reportJournal of the International Society of Sports NutritionResearch PaperAltitude, mountain, ski, trail running, nutritional intervention, dietary supplements, ergogenic aids
Emanuel E. Canfora,Gerben D.A. Hermes, Mattea M?ller,Jacco Bastings,Elaine E. Vaughan,Marco A. van Den Berg,Jens J. Holst, Koen Venema,Erwin G. Zoetendal & Ellen E. Blaak2021Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic menGut Microbes Research PaperShort-chain fatty acids, dietary fibers, gut microbiota, substrate metabolism
Rens L.J.van Meijel, Max A.A.Vogel, Johan W.E.Jocken, Lars M.M.Vliex, Joey S.J.Smeets, Nicole Hoebers, Joris Hoeks, Yvonne Essers, Paul F.M.Schoffelen. Henrike Sell, Sander Kersten, Kasper M.A. Rouschop, Ellen E.Blaak, Gijs H. Goossens2021Mild intermittent hypoxia exposure induces metabolic and molecular adaptations in men with obesityMolecular MetabolismResearch PaperHypoxia exposure, Obesity, Insulin sensitivity, Substrate metabolism, Inflammation, RCT
Froukje Vanweert, Marlies de Ligt, Joris Hoeks, Matthijs K C Hesselink, Patrick Schrauwen, Esther Phielix20202 Diabetes–Related Metabolic DisturbancesThe Journal of Clinical Endocrinology & MetabolismResearch Paperbranched-chain amino acids, type 2 diabetes, mitochondrial oxidative capacity, first-degree relatives, insulin resistance, 1-13C leucine oxidation
Yvo J.M. Op den Kamp; Marlies de Ligt; Bas Dautzenberg; Esther Kornips; Russell Esterline; Matthijs K.C. Hesselink ; Joris Hoeks; Vera B. Schrauwen-Hinderling; Bas Havekes; Jan Oscarsson; Esther Phielix; Patrick Schrauwen2021Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial Diabetes CareResearch PaperDiabetes, Metabolism, EE
L. Grevendonk, N. J. Connell, C. McCrum, C. E. Fealy, L. Bilet, Y. M. H. Bruls, J. Mevenkamp, V. B. Schrauwen-Hinderling, J. A. J?rgensen, E. Moonen-Kornips, G. Schaart, B. Havekes, J. de Vogel-van den Bosch, M. C. E. Bragt, K. Meijer, P. Schrauwen & J. Hoeks2021Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical functionNature Communications Research Paperskeletal muscle, mitochondrial capacity, aging, energy metabolism, energy metabolism, exercise
Adam Jake Sellers, Hannah Pallubinsky, Pascal Rense, Wouter Bijnens, Tineke van de Weijer, Esther Moonen-Kornips, Patrick Schrauwen, and Wouter D. van Marken Lichtenbelt2021The effect of cold exposure with shivering on glucose tolerance in healthy menJournal of applied physiologyResearch Papercold-induced thermogenesis, glucose metabolism, insulin sensitivity, oral glucose tolerance test, thermoregulation
Carlijn M. E. Remie, Michiel P. B. Moonen, Kay H. M. Roumans, Emmani B. M. Nascimento, Anne Gemmink, Bas Havekes, Gert Schaart, Esther Kornips, Peter J. Joris, Vera B. Schrauwen-Hinderling, Joris Hoeks, Sander Kersten, Matthijs K. C. Hesselink, Esther Phielix, Wouter D. van Marken Lichtenbelt & Patrick Schrauwen2021Metabolic responses to mild cold acclimation in type 2 diabetes patientsNature Communications Research PaperDiabetes
Endocrine system and metabolic diseases
Jan-Frieder Harmsen, Jakob Wefers, Daniel Doligkeit, Luc Schlangen, Bas Dautzenberg, Pascal Rense, Dirk van Moorsel, Joris Hoeks, Esther Moonen-Kornips, Marijke C. M. Gordijn, Wouter D. van Marken Lichtenbelt & Patrick Schrauwen2022The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of dayDiabetologiaResearch PaperBiological clock, Circadian rhythm, Glucose intolerance, Insulin resistance, Light at night, Light exposure, Melatonin, Postprandial metabolism, Sleeping metabolic rate
M.A. Gonz?lez Hern?ndez, E.E. Canfora and E.E. Blaak2021Faecal microbial metabolites of proteolytic and saccharolytic fermentation in relation to degree of insulin resistance in adult individualsBeneficial MicrobesResearch Papergut-derived metabolites, insulin sensitivity, excessive body weight
Yoanna M.Ivanova, Hannah Pallubinsky, Rick Kramer, Wouter van Marken Lichtenbelt2021The influence of a moderate temperature drift on thermal physiology and perceptionPhysiology & BehaviorResearch PaperThermal physiology, Thermal comfort, Thermal sensation, Body temperature, Energy metabolism, Drifting temperature
Carlijn M. E. Remie, Georges E. Janssens, Lena Bilet, Michel van Weeghel, Bernard M. F. M. Duvivier, Vera H. W. de Wit, Niels J. Connell, Johanna A. J?rgensen, Bauke V. Schomakers, Vera B. Schrauwen-Hinderling, Joris Hoeks, Matthijs K. C. Hesselink, Esther Phielix, Riekelt H. Houtkooper & Patrick Schrauwen2021Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal womenDiabetologiaResearch PaperClinical trial, Exercise, Insulin sensitivity, Metabolomics, Muscle metabolism, Sedentary time, Sitting, Sitting less
Carlijn M.E. Remie, Michiel P.B. Moonen, Kay Roumans, Niels J. Connell, Bas Havekes, Anne Gemmink, Emmani B.M. Nascimento, Gert Schaart, Esther Kornips, Peter J. Joris, Vera B.Schrauwen-Hinderling, Joris Hoeks, Sander Kersten, Matthijs K.C. Hesselink, Esther Phielix,
Wouter D. van Marken Lichtenbelt, Patrick Schrauwen
2021Non-shivering cold acclimation does not improve postprandial metabolism or insulin sensitivityNature Communications Research Papermetabolism, insulin sensitivity
N J Connell, L Grevendonk, C E Fealy, E Moonen-Kornips, Y M H Bruls, V B Schrauwen-Hinderling, J de Vogel, R Hageman, J Geurts, R Zapata-Perez, R H Houtkooper, B Havekes, J Hoeks, P Schrauwen2021NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older AdultsThe Journal of NutritionResearch PaperNAD+-precursors, skeletal muscle, mitochondrial function, older adults, metabolism, muscle health
Anouk Gijbels, Inez Trouwborst, Kelly M. Jardon, Gabby B. Hul, Els Siebelink, Suzanne M. Bowser, Dilemin Yildiz, Lisa Wanders, Bal?zs Erdos, Dick H. J. Thijssen, Edith J. M. Feskens, Gijs H. Goossens, Lydia A. Afman and Ellen E. Blaak2021The PERSonalized Glucose Optimization Through Nutritional Intervention (PERSON) Study: Rationale, Design and Preliminary Screening ResultsFrontiers in NutritionResearch Paperprecision nutrition, personalized nutrition, insulin resistance, metabolic phenotype, glucose homeostasis, obesity, dietary intervention study, randomized clinical trial
Niels J. Connell, Daniel Doligkeit, Charlotte Andriessen, Esther Kornips-Moonen, Yvonne M. H. Bruls, Vera B. Schrauwen-Hinderling, Tineke van de Weijer, Wouter D. van Marken-Lichtenbelt, Bas Havekes, Lawrence Kazak, Bruce M. Spiegelman, Joris Hoeks & Patrick Schrauwen2021No evidence for brown adipose tissue activation after creatine supplementation in adult vegetariansResearch PaperFat metabolism, Homeostasis, Randomized controlled trials
Georges E. Janssens, Lotte Grevendonk, Ruben Zapata Perez, Bauke V. Schomakers, Johan de Vogel-van den Bosch, Jan M. W. Geurts, Michel van Weeghel, Patrick Schrauwen, Riekelt H. Houtkooper & Joris Hoeks2022Healthy aging and muscle function are positively associated with NAD+ abundance in humansNature AgingResearch PaperAgeing, Energy metabolism, Metabolomics
Huiwen Xu, Antonio Martinez-Nicolas, Wendy D. Martinez-Avilad, Juan M.A.Alcantara Juan Corral-Perez. David Jimenez-Pavon, Francisco M.Acosta, Jonatan R.Ruiz, Borja Martinez-Tellez2021Impact of an intermittent and localized cooling intervention on skin temperature, sleep quality and energy expenditure in free-living, young, healthy adults
Rodrigo Mancilla,Bram Brouwers,Vera B. Schrauwen-Hinderling,Matthijs K. C. Hesselink,Joris Hoeks,Patrick Schrauwen2020Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humansPhysiological ReportsResearch Paperadipose tissue insulin sensitivity, hyperinsulinemic-euglycemic clamp, skeletal muscle insulin sensitivity, timing of exercise
Sabine Daemen, Anne Gemmink, Alexandra Paul, Nils Billecke, Katrina Rieger, Sapun H. Parekh, Matthijs K. C. Hesselink2020Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetesDiabetologiaAthlete’s paradox, CARS microscopy, Intramyocellular lipid storage, Lipid composition, Lipid droplet chemical
composition, Lipid droplets, Type 2 diabetes
Yvonne M. H. Bruls,Yvo J. M. op den Kamp,Esther Phielix,Lucas Lindeboom,Bas Havekes,Gert Schaart,Esther Moonen-Kornips,Joachim E. Wildberger,Matthijs K. C. Hesselink,Patrick Schrauwen,Vera B. Schrauwen-Hinderling2020L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibilityPLoS ONE10.1371/journal.pone.0239506
Tay SH, Goh HJ, Govindharajulu P, Cheng J, Camps SG, Haldar S, Velan SS, Sun L, Li Y, Henry CJ, Leow MK2020Brown fat activity determined by infrared thermography and thermogenesis measurement using whole body calorimetry (BRIGHT Study)Physiol ResBrown adipose tissue, Infrared thermography, Calorimetry,
Thermogenesis, Automation
Jakob Wefers, Niels J. Connell, Ciar?n E. Fealy, Charlotte Andriessen, Vera de Wit, Dirk van Moorsel, Esther Moonen-Kornips, Johanna A. J?rgensen, Matthijs K.C. Hesselink, Bas Havekes, Joris Hoeks, Patrick Schrauwen
2020Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individualsMol MetabMitochondria; Skeletal muscle; Daynight rhythm; Insulin resistance10.1016/j.molmet.2020.101050
Javier T. Gonzalez, Marlou L. Dirks, Andrew M. Holwerda, Imre W.K. Kouw, Luc J.C. van Loon2020Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short‑term bed restEur J Appl PhysiolGlucagon; Glucagonlike peptide1; Glucose; Insulin; Insulin sensitivity; Metabolism10.1007/s00421-020-04431-4
Alberto G. Bonomi, Gill A. ten Hoor, Helma M. de Morree, Guy Plasqui, Francesco Sartor2020Cardiorespiratory fitness estimation from heart rate and body movement in daily lifeJ Appl Physiolactivity classification; energy expenditure; maximal aerobic power;
Marlies de Ligt, Maaike Bergman, Rodrigo Mancilla Fuentes, Hans Essers, Esther Moonen-Kornips, Bas Havekes, Vera B Schrauwen-Hinderling, Patrick Schrauwen2020No effect of resveratrol supplementation after 6 months on insulin sensitivity in overweight adults: a randomized trialAm J Clin Nutrresveratrol; insulin resistance; intrahepatic lipid content; glycemic control; obesity10.1093/ajcn/nqaa125
Mattea M?ller, Gerben D. A. Hermes, Emanuel E. Canfora, Jens J. Holst, Erwin
G. Zoetendal, Hauke Smidt, Freddy Troost, Frank G. Schaap, Steven Olde Damink, Johan W. E. Jocken, Kaatje Lenaerts, Ad A. M. Masclee, Ellen E. Blaak
2020Effect of wheat bran derived prebiotic supplementation on gastrointestinal transit, gut microbiota, and metabolic health: a randomized controlled trial in healthy adults with a slow gut transit
Gut MicrobesResearch Paper/ReportGastrointestinal transit; Gut microbiota; Prebiotic; Energy metabolism; Gut Hormones; ArabinoxylanOligosaccharides; Stool consistency10.1080/19490976.2019.1704141
Hannah Pallubinsky, Esther Phielix, Bas Dautzenberg, Gert Schaart, Niels J. Connell, Vera de Wit-Verheggen, Bas Havekes, Marleen A.van Baak, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt2020Passive exposure to heat improves glucose metabolism in overweight humansActa PhysiologicaRegular Paperfat metabolism; glucose homeostasis; heat acclimation; liver metabolism; substrate oxidation; thermoregulation10.1111/apha.13488
Marije te Kulve, Luc J. M. Schlangen, Wouter D. van Marken Lichtenbelt2019Early evening light mitigates sleep compromising physiological and alerting responses to subsequent late evening lightSci Rep10.1038/s41598-019-52352-w
H. Pallubinsky, L. Schellen, W.D. van Marken Lichtenbelt2019Exploring the human thermoneutral zone – A dynamic approachJ Therm Biol10.1016/j.jtherbio.2018.12.014
Eva Fechner, Lena Bileta, Harry P.F. Peters, Harry Hiemstra, Doris M. Jacobs, Cara Op ‘t Eyndt, Esther Kornips, Ronald P. Mensink, Patrick Schrauwen2019Effects of a whole diet approach on metabolic flexibility, insulin sensitivity and postprandial glucose responses in overweight and obese adults – A randomized controlled trialClin Nutr ESPENClinical TrialDietary intervention; Insulin resistance; Hyperinsulinemic euglycemic clamp; Mixed meal challenge; Postprandial metabolism; Obesity10.1016/j.clnu.2019.12.010
Marlou L. Dirks, Joey S. J. Smeets, Andrew M. Holwerda, Imre W. K. Kouw, Gabriel N. Marzuca-Nassr, Annemie P. Gijsen, Graham P. Holloway, Lex B. Verdijk, Luc J. C. van Loon2019Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed restAm J Physiol Endocrinol MetabClinical Trialmuscle atrophy; muscle disuse; enteral feeding; nutrition; tube feeding10.1152/ajpendo.00378.2018
Jose J. van den Driessche, Jogchum Plat, Guy Plasqui, Ronald P. Mensink2019A Single Dose of Goji Berries Does Not Affect Postprandial Energy Expenditure and Substrate Oxidation in Healthy, Overweight MenHindawi J Nutr MetClinical Study10.1155/2019/4057143\
Mattea M?ller, Manuel A. Gonz?lez Hern?ndez, Gijs H. Goossens, Dorien Reijnders, Jens J. Holst, Johan W. E. Jocken, Hans van Eijk, Emanuel E. Canfora, Ellen E. Blaak2019Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humansSci Rep10.1038/s41598-019-48775-0
Yvonne MH Bruls, Marlies de Ligt, Lucas Lindeboom, Esther Phielix, Bas Havekes, Gert Schaart, Esther Kornips, Joachim E Wildberger, Matthijs KC Hesselink, Deborah Muoiod, Patrick Schrauwen, Vera B Schrauwen-Hinderling2019Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trialEBioMedicineLcarnitine; Metabolic flexibility; Insulin sensitivity; Acetylcarnitine; Impaired glucose tolerance; Hyperinsulinemiceuglycemic clamp10.1016/j.ebiom.2019.10.017
Jordi P.D. Kleinloog, Ronald P. Mensink, Dimo Ivanov, Jos J. Adam, Kamil Uludağ and Peter J. Joris2019Aerobic Exercise Training Improves Cerebral Blood Flow and Executive Function: A Randomized, Controlled Cross-Over Trial in Sedentary Older MenFront Aging Neurosciaging; arterial spin labeling; cerebral blood flow; cognition; exercise; glucose metabolism10.3389/fnagi.2019.00333
Saartje Straetemans, D.A. Schott, Guy Plasqui, Hilde Dotremont, Angèle J.G.M. Gerver‑Jansen, An Verrijken, Klaas Westerterp, Luc J.I. Zimmermann, Willem‑Jan M. Gerver2019Effect of growth hormone treatment on energy expenditure and its relation to first-year growth response in childrenEur J Appl PhysiolEnergy expenditure; Body composition; Metabolism; Growth hormone treatment; Children; Firstyear
growth response
Marlou L. Dirks, Paula M. Miotto, Gijs H. Goossens, Joan M.Senden, Heather L. Petrick, Janneau van Kranenburg, Luc J.C. van Loon and Graham P. Holloway2019Short-term bed rest-induced insulin resistance cannot beexplained by increased mitochondrial H2O2emissionJ Physiol10.1113/JP278920
Paul F.M. Schoffelen, Marcel den Hoed, Eric van Breda, Guy Plasqui2019Test‐retest variability of VO2max using total‐capture indirect calorimetry reveals linear relationship of VO2 and PowerScand J Med Sci Sportsbreath‐by‐breath; exercise testing; gas exchange; intra‐individual variability; validation10.1111/sms.13324
Minela Haskovic, Britt Derks, Liesbeth van der Ploeg, Jorn Trommelen, Jean Nyakayiru, Luc JC van Loon, Sabrina Mackinnon, Wyatt W Yue, Roy WA Peake, Li Zha, Didem Demirbas, Wanshu Qi, Xiaoping Huang, Gerard T Berry, Jelle Achten, J?rgen Bierau, M Estela Rubio-Gozalbo, Ana I Coelho2018Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemiaOrphanet J Rare DisAmino acid supplementation; Arginine; Chemical chaperones; Classic galactosemia; Galactose metabolism; Inherited metabolic disorder10.1186/s13023-018-0954-8
Marije Te Kulve, Luc Schlangen, Lisje Schellen, Jan L Souman, Wouter van Marken Lichtenbelt 2018Correlated colour temperature of morning light influences alertness and body temperaturePhysiol. Behav.Randomized Controlled TrialAlertness; Body temperature; Light spectrum; Perceived comfort; Reaction times; Thermophysiology10.1016/j.physbeh.2017.12.004
Christina M. van der Beek, Emanuel E. Canfora, Anna M. Kip, Stefan H.M. Gorissen, Steven W.M. Olde Damink, Hans M. van Eijk, Jens J.Holst, Ellen E. Blaak, Cornelis H.C. Dejong, Kaatje Lenaerts2018The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese menMetab Clin ExpClinical TrialMicrobiota; Prebiotic; Obesity; Fat oxidation; Acetate10.1016/j.metabol.2018.06.009
Jakob Wefers, Dirk van Moorsel, Jan Hansen, Niels J Connell, Bas Havekes, Joris Hoeks, Wouter D van Marken Lichtenbelt, H?l?ne Duez, Esther Phielix, Andries Kalsbeek, Mark V Boekschoten, Guido J Hooiveld, Matthijs KC Hesselink, Sander Kersten, Bart Staels, Frank AJL Scheer, Patrick Schrauwen2018Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscleProc Natl Acad Sci USAcircadian misalignment; shift work; diabetes; insulin sensitivity;skeletal muscle10.1073/pnas.1722295115
Marije te Kulve, Luc Schlangen, Lisje Schellen, Jan L. Souman, Wouter van Marken Lichtenbelt2018Correlated colour temperature of morning light influences alertness and body temperaturePhysiol BehavAlertness; Light spectrum; Body temperature; Reaction times; Thermophysiology; Perceived comfort10.1016/j.physbeh.2017.12.004
Gill A. ten Hoor, Guy Plasqui, Annemie M.W.J. Schols, Gerjo Kok 2018A Benefit of Being Heavier Is Being Strong: a Cross-Sectional Study in Young AdultsSports Med OpenOverweight; Body composition; Strength; Motivation; Attitude10.1186/s40798-018-0125-4
Bram Brouwers, Vera B. Schrauwen-Hinderling, Tomas Jelenik, Anne Gemmink, Lauren M. Sparks, Bas Havekes, Yvonne Bruls, Dennis Dahlmans, Michael Roden, Matthijs K.C. Hesselink, Patrick Schrauwen2018Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liverAm J Physiol Endocrinol Metabhyperinsulinemiceuglycemic clamp; insulin resistance; magnetic resonance spectroscopy10.1152/ajpendo.00266.2017
Marije te Kulve, Luc Schlangen, Wouter van Marken Lichtenbelt2018Interactions between the perception of light and temperatureIndoor Airambient temperature; correlated color temperature; indoor environment; light intensity; thermal comfort; visual comfort10.1111/ina.12500
Parastoo Fazelzadeh, Huub C.J. Hoefsloot, Thomas Hankemeier, Jasper Most, Sander Kersten, Ellen E. Blaak, Mark Boekschoten, John van Duynhoven 2018Global testing of shifts in metabolic phenotypeMetabolomicsGoeman’s global test; Metabolic pathways; Phenotype shifts10.1007/s11306-018-1435-8
Anne Gemmink, Sabine Daemen ,Bram Brouwers, Peter R. Huntjens, Gert Schaart, Esther Moonen-Kornips, Johanna Jorgensen, Joris Hoeks, Patrick Schrauwen, Matthijs K.C. Hesselink2018Dissociation of intramyocellular lipid storage and insulinresistance in trained athletes and type 2 diabetes patients;involvement of perilipin 5?J Physiol10.1113/JP275182
Rosanne J.H.C.G. Beijers, Stephanie M.D. Huysmans, Coby van de Bool, Boris R.M. Kingma, Lex B. Verdijk, Luc J.C. van Loon, Steven J.R. Meex, Harry R.Gosker, Annemie M.W.J. Scholsa2018The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary diseaseClin Nutr ESPENBlood pressure; COPD; Cardiac biomarkers; Dietary nitrate; Mechanical efficiency10.1016/j.clnu.2017.10.011
Sepideh Kaviani, Dale A Schoeller, Eric Ravussin, Edward L Melanson, Sarah T Henes, Lara R Dugas, Ronald E Dechert, George Mitri, Paul FM Schoffelen, Pim Gubbels, Asa Tornberg, Stephen Garland, Marco Akkermans, Jamie A Cooper2018Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion TechniqueNutr Clin PractComparative Studyaccuracy; energy metabolism; indirect calorimetry; metabolic cart; methanol; reliability10.1002/ncp.10070
Sabine Daemen, Anne Gemmink, Bram Brouwers, Ruth C.R. Meex, Peter R. Huntjens, Gert Schaart, Esther Moonen-Kornips, Johanna J?rgensen, Joris Hoeks, Patrick Schrauwen, Matthijs K.C. Hesselink2018Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradoxMol MetabInsulin sensitivity; Athlete’s paradox; Intramyocellular lipid; Lipid droplets10.1016/j.molmet.2018.08.004
Bram Brouwers, Vera B Schrauwen-Hinderling, Tomas Jelenik, Anne Gemmink, Lauren M Sparks, Bas Havekes, Yvonne Bruls, Dennis Dahlmans, Michael Roden, Matthijs KC Hesselink, Patrick Schrauwen2018Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liverAm J Physiol Endocrinol MetabControlled Clinical Trialhyperinsulinemiceuglycemic clamp; insulin resistance; magnetic resonance spectroscopy10.1152/ajpendo.00266.2017
Marlies de Ligt, Yvonne M.H. Bruls, Jan Hansen, Marie-Fleur Habets, Bas Havekes, Emmani B.M. Nascimento, Esther Moonen Kornips, Gert Schaart, Vera B. Schrauwen-Hinderling, Wouter van Marken Lichtenbelt, Patrick Schrauwen2018Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetesMol MetabClinical TrialResveratrol; Type 2 diabetes; Prediabetes; Insulin sensitivity; Mitochondrial function; Brown adipose tissue10.1016/j.molmet.2018.04.004
Jorn Trommelen, Cas J Fuchs, Milou Beelen, Kaatje Lenaerts, Asker E Jeukendrup, Naomi M Cermak, Luc J C van Loon2017Fructose and Sucrose Intake Increase Exogenous Carbohydrate Oxidation during ExerciseNutrientsRandomized Controlled Trialsubstrate utilization; metabolism; stable isotopes; sugar10.3390/nu9020167
Dajo Sanders, Tony Myers, Ibrahim Akubat2017Training-Intensity Distribution in Road Cyclists: Objective Versus Subjective MeasuresInt J Sports Physiol Performblood lactate; cycling; heart rate; rating of perceived exertion; training impulse10.1123/ijspp.2016-0523
Dajo Sanders, Grant Abt, Matthijs K C Hesselink, Tony Myers, Ibrahim Akubat2017Methods of Monitoring Training Load and Their Relationships to Changes in Fitness and Performance in Competitive Road CyclistsInt J Sports Physiol Performcycling; endurance; heart rate; power output; training impulse10.1123/ijspp.2016-0454
Bram Brouwers, Vera B. Schrauwen-Hinderling, Tomas Jelenik, Anne Gemmink, Bas Havekes, Yvonne Bruls, Dennis Dahlmans, Michael Roden, Matthijs K.C. Hesselink, Patrick Schrauwen2017Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetesClin Sci (Lond)10.1042/CS20170261
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M Mensink,?M K C Hesselink,?A P Russell,?G Schaart,?J-P Sels,?P Schrauwen2007Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitusInt J Obes (Lond)Controlled Clinical Trialinsulin resistance; skeletal muscle; intramyocellular lipid; PGC1a; thiazolidinediones; metabolic flexibility10.1038/sj.ijo.0803567
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